★★★★★ Rated Very Good (17,391 Reviews)

Pup Plus™ Anti-Aging NAD+ Drops || Veterinarian Recommended 🏥

LIMITED TIME - SALE ENDS TONIGHT

Give your dog 2-4 extra healthy years with Pup Plus™—powered by the CanineNAD+ Renew™ Complex: pharmaceutical-grade Nicotinamide Riboside (NAD+ precursor) + PQQ (mitochondrial builder) + CoQ10 (organ protector). Slow cellular aging, restore energy, and help your dog feel years younger—backed by our 180-Day Tail-Wag Promise.


Over 200,000 Dogs Have Experienced:

More energy and playfulness (even in senior dogs)

Easier movement—stairs, jumping, longer walks

Brighter eyes and shinier coat

Improved organ function and reduced inflammation

Acting "years younger" within 6-8 weeks

Slowed biological aging at the cellular level

180-Day Money-Back Guarantee

Made in and Ships from The USA

"My Dog Is Slowing Down… He Struggles With Stairs, Sleeps All Day, and Barely Plays Anymore. The Vet Says 'He's Just Getting Old.' Is There Really Nothing I Can Do?"

Aging, joint decline, and organ deterioration can steal your dog's energy, mobility, and joy—turning every year into what feels like seven. You watch them struggle to stand, lose interest in walks, and sleep through days that used to be full of life. It's heartbreaking.


And the usual "solutions"? They're band-aids that never fix the real issue inside your dog's cells.

Joint supplements? They reduce inflammation but don't address the cellular energy crisis causing muscles to weaken and organs to fail.

Senior dog food? Adjusts calories for less activity but can't rebuild the dying mitochondria in every cell.

Pain medications? Mask discomfort but do nothing to slow the biological aging clock ticking down your dog's remaining years.

That's why so many dog owners watch their pets decline year after year, thinking nothing works… until they address what's really happening at the cellular level.

The Veterinary Industry Has Been Lying To You!

You've been sold symptom management instead of cellular aging solutions.


For decades, the pet industry has trained you to accept that "dogs just age fast"—that a 10-year lifespan is "normal" for some breeds, that stiffness and organ failure are "inevitable."


But here's what they're not telling you:

Your dog isn't aging because of their breed, size, or bad luck. They're aging because their cells are running out of NAD+—the master molecule that controls how fast the biological clock runs.

Conventional vet treatments focus on:

  • Managing symptoms after organs start failing
  • Treating diseases once they appear
  • Prescribing pain meds to make decline "more comfortable"

Conventional vet treatments DO NOT focus on:

  • Measuring or restoring NAD+ levels
  • Preventing cellular aging before disease starts
  • Slowing the biological aging process itself

The result? You're paying for band-aids while your dog's cells continue starving for energy—and their remaining years tick away faster than they should.

When Your Dog's Body is Failing Them…

Turn to clinically-backed, veterinarian-developed ingredients to restore cellular energy and slow biological aging—naturally.

What Happens When Your Dog's Cells Aren't Properly Nourished?

Energy crashes and sleep increases (mitochondria dying)
Mobility declines—stairs become mountains (muscle cells deteriorating)
Eyes cloud and coat dulls (oxidative stress accumulating)
Organs begin failing (liver, kidneys, heart running on fumes)
Cognitive decline—confusion, less engagement (brain cells starving)
Chronic inflammation spreads (cellular cleanup systems offline)
Your dog's biological age accelerates toward their final years

When Your Body is Failing You…

Turn to clinically-backed, natural ingredients to restore deep, unbroken sleep—night after night.

Introducing

Pup Plus™ Anti-Aging NAD+ Drops

A Natural, Science-Backed Daily Ritual to Slow Cellular Aging and Give Your Dog More Healthy Years

For years, dog owners have been told that joint chews, senior formulas, or prescription meds are the only ways to help aging dogs…


But those fixes either mask symptoms, stop working, or never address the root cause—without restoring the cellular energy your dog needs to stay young.


Pup Plus™ Anti-Aging NAD+ Drops was created to change that—a veterinarian-developed, human-grade formula designed to work from the inside out so your dog feels more energetic, moves easier, and lives longer. So… what makes Pup Plus different?

At the heart of our formula is pharmaceutical-grade Nicotinamide Riboside (NR)

The same NAD+ precursor used in Harvard longevity studies and human anti-aging clinics.

This isn't some cheap supplement with unproven ingredients. NR is clinically shown to raise NAD+ levels, restore mitochondrial function, and slow biological aging in mammals—including dogs.

By age 7, most dogs have lost 60-70% of their natural NAD+ levels. Their cells are literally starving for energy. NR replenishes that missing fuel, giving your dog's cells the power to:

✅ Repair DNA damage before it becomes disease
✅ Produce more cellular energy (ATP)
✅ Activate "longevity genes" (sirtuins) that slow aging
✅ Reduce chronic inflammation
✅ Support organ function (heart, liver, kidneys, brain)

But NR isn't the only powerhouse at work…

We pair it with PQQ (Pyrroloquinoline Quinone)

The "mitochondrial builder" that creates NEW energy factories inside cells.

Think of it this way:

  • NR charges your dog's existing cellular batteries
  • PQQ helps build NEW batteries

Together, they don't just restore energy—they expand your dog's capacity for energy, so they don't just feel "a bit better"—they feel like they have backup engines.

Plus CoQ10 (Ubiquinol Form)

The organ protector that keeps your dog's heart, liver, and kidneys functioning optimally.

Every heartbeat, every jump, every sprint to greet you at the door runs through CoQ10. As dogs age, CoQ10 levels plummet—leaving organs vulnerable to oxidative stress and failure.

Pup Plus restores CoQ10 levels to protect the organs that keep your dog alive.


And We Didn't Stop There:

Omega-3 DHA/EPA - Reduces inflammation, supports brain health, improves mobility
Taurine - Essential for heart health (especially breeds prone to heart issues)
Astaxanthin - Super antioxidant (6,000x more powerful than Vitamin C)
Natural Liver Flavoring - Dogs actually LOVE taking it (no fighting or hiding pills)


This Gentle Daily Formula Has Become the Canine Longevity "Holy Grail"

"For years I watched dog owners cycle through joint supplements, senior formulas, and pain meds—spending hundreds while their dogs continued declining. When I began using pharmaceutical-grade NAD+ precursors (what Pup Plus calls CanineNAD+ Renew™), everything changed. Dogs showed measurable improvements in energy, mobility, organ function, and biological age markers—no prescriptions, no side effects, no decline. It's the most powerful longevity intervention I've seen in 20 years of veterinary practice."


- Dr. Sarah Mitchell, DVM Board-Certified Veterinarian | 20+ Years Specializing in Canine Longevity

Why Your Dog's Cellular Health Matters…

Most "solutions" only mask decline. Joint supplements reduce inflammation temporarily. Senior formulas adjust calories for less activity. Pain meds numb discomfort—but do nothing to slow the aging clock.


Pup Plus™ restores cellular aging from the inside. Pharmaceutical-grade NAD+ precursors refuel dying mitochondria. PQQ builds new energy factories. CoQ10 protects organs. Omega-3s reduce inflammation. Taurine supports heart function.

No complicated routines. No dependence. Just measurable cellular rejuvenation that shows up in bloodwork and behavior.

Ideal For:

👉 Dogs age 7+ experiencing energy decline

👉 Senior dogs with mobility issues (stairs, jumping, stiffness)

👉 Breeds with short lifespans (Golden Retrievers, Great Danes, etc.)

👉 Dogs with early signs of organ decline (bloodwork changes)

👉 Cognitive decline or "doggy dementia"

👉 Post-surgery recovery or chronic health issues

👉 Any dog owner who wants to maximize their dog's healthy years

👉 Overall Cellular Longevity Support

 ● Sale: Live for 24 Hrs | Stock: only 58 Boxes left

Discover The Remarkable Purity Of Our Formula

Support their body from within, restore cellular energy naturally, and skip the band-aid solutions that never address aging—so your dog can feel years younger, move easier, and give you precious extra time together.

Ingredients

NR - NAD+ Precursor

Nicotinamide Riboside (NR) is the same molecule used in Harvard longevity studies. Clinically shown to raise NAD+ levels, restore mitochondrial function, and slow biological aging. Safely dosed for canine biology—this is the cellular fuel your dog's been missing.

PQQ - Mitochondrial Builder

Stimulates creation of NEW mitochondria (cellular power plants). Known as "the spark plug for aging cells"—it doesn't just restore energy, it expands your dog's capacity for it.

CoQ10 - Organ Protector

Protects heart, liver, and kidneys from age-related decline. Essential for cellular energy production and preventing oxidative damage to vital organs.

Omega-3 - Inflammation Fighter

Reduces chronic inflammation that accelerates aging. Supports brain health, cognitive function, joint comfort, and skin/coat quality.

Taurine - Cardiac Guardian

Essential for heart health (especially in breeds prone to DCM). Supports eye health, prevents age-related decline, and provides anti-fatigue support.

Astaxanthin - Super Antioxidant

6,000x more powerful than Vitamin C. Protects cells from oxidative stress, supports immune strength, and reduces cellular damage from aging.

What to expect after 16 weeks of consistent use?

iconWeek two

You start to notice subtle changes—your dog seems more alert, appetite improves, and they're slightly more interested in their surroundings. Cellular energy restoration has begun.

iconWeek four

Get excited. Energy levels noticeably increase. Stairs are easier. Walks last longer. Eyes look brighter. Coat starts getting shinier. You're seeing the first visible signs of cellular rejuvenation.

iconWeek six

Hello, real transformation. The "old dog" pattern fades. Your dog brings you toys again, wants to play, moves with less stiffness. Mornings feel energetic; afternoons don't drag.

iconWeek eight

Noticeably more vitality—even after active days. You see more engagement, responsiveness, and joy. Friends and family comment: "What did you do? He looks years younger!"

iconWeek twelve

The routine is locked in. Energy is consistent, mobility is dramatically improved, and bloodwork (if you test) shows measurable improvements in organ function and inflammation markers.

iconWeek sixteen

Long-term cellular rejuvenation has arrived. Your dog's biological age may have actually DECREASED. Keep going and the benefits continue compounding with each month.

And the best part?
The longer you stay consistent with Pup Plus™, the more years you're potentially adding to your dog's healthy lifespan.

How to Use

And the Best Part Is, You Don’t Have to Decide Today!
Simply Try It for 180 Days - Risk-FREE - and See What Happens

Here’s the deal:

We believe in Pup Plus™ so much that we don't want you to spend a dime until you're 100% certain it works for your dog.

That's why we offer a 180-day tail-wag guarantee—no questions asked.

If you don't notice increased energy, improved mobility, a shinier coat, and your dog acting years younger, we'll issue you a full refund—no hassle, no stress.

In other words, you're only paying if Pup Plus transforms your dog's life.

And from the thousands of dog owners who have already experienced life-changing results… we're confident it will.

What People, Just Like You, Are Saying About Pup Plus™

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Lisa.

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I love this product. It took a couple of months to restore moisture but it’s possible now to be intimate with my husband without looking for lubricants to help. I just feel better as well.

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Alexia.

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Sea Buckthorn is renowned for its ability to alleviate feminine dryness without estrogen. Compared to the price of some estrogen replacement therapies, these capsules offer a cost effective alternative. In addition to the value, the proprietary blend also contains many other nutrients such as Vitamins A & E and Omega 3,6,7, and 9 that may not only help with feminine dryness, but are also great for your skin and hair. These capsules are a reasonable size and easy to swallow, and leave out the harmful ingredients of many similar options. Overall, this product could be great solution to those suffering from feminine dryness/itching/discomfort without the hassle and mess of physical lubricant or the cost of more expensive solutions.

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Sarah.

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After reading some of the reviews, I decided to give this product a try, since I try a whole bunch of other things with no success. When I tell tou it works, it really works. My dryness was so bad that it would burn like crazy when I was having intimacy with my husband making it extremely uncomfortable at times. I was happy to had found this product, that was life changing for me.

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Lola.

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Easy to swallow. Changes were felt after three weeks of taking it. Will purchase again.

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Sarah.

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I will admit I do not take these as instructed. I take one in the morning and one at night. And it’s key to take every day. Once I started taking them everyday I started feeling the results almost immediately. Even when I’m not aroused I can feel “she’s” more moist than ever! Sex is incredible now!! I’m stocking up because I don’t ever want to run out of them!!

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Rachel.

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Only 3 words....It really works!

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Susan.

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I really didn’t expect a pill to help with post menopausal dryness. I am pleasantly surprised, I am naturally producing lubrication once again. No more uncomfortable dryness.

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Grace.

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I don’t normally post reviews but this product has changed my life.. I’ve been taking it consistently for 1 month and I’ve already started to see so many changes with my body. I was experiencing dryness within my body so I started to do some research.. I came across lubracil and I honestly cannot believe the benefits this product has had on me. I would highly recommend giving this product a try.. be consistent and you will see the changes!

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Sharon.

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After an intense evening my lady was pissed! You know the attitude ladies, post menopausal, Ms. Vajayjay gets irritated, swollen, throbbing intense discomfort! I started searching ideas, something had to help! I came across these supplements. I started two tablets daily. After 4 days it's getting a little more hospitable. Next week maybe the coconut oil won't be the 1st thing I grab! Lol

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Tiamia83.

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I have been taking this product for ten days. I am already noticing results. I was in a lot of pain during and after intimacy with my husband. Now I just have a little bit of stinging sensation. I did try borax pills. I didn’t like the grainy feeling.

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Petrecia.

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That's an awesome pill! Because of the gel form and the ideal size, it is easy to consume. It's also fantastic because it's made with natural ingredients. It performs its function as intended. Considering the price, I think it is excellent value.

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Olivia.

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This has been my lifesaver! I was experiencing horrible dryness in my private parts by most importantly internally, I was really desperate to find a solution since I was unable to sleep because of it. I have been using this product for almost one month and I am planning to use it for 2 months as recommended. After that time, I will determine if I need to keep using it but this has been everything I was looking for!

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Helen F.

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Didn't think it would work, but to my surprise it does! On my 3rd box

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Alice.

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I am here to tell you this works!! I had started experiencing dryness, discomfort, itchiness, pain from how swiftly our bodies start drying out/up from menopause. This product will reverse the clock back decades! No more symptoms AND from and ALL NATURAL product. I couldn’t take any HRTs due to a heart condition, so this was the only thing I had left to try. I am SO thrilled it works and will be using it for life! Try it, you will not be disappointed!

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Ava.

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I just started these pills 6 days ago. My symptoms have been dryness, pain, and itching. These symptoms have affected to be in the mood on a consistent basis. I just had the best experience with my husband that I've had in a long time. I will be getting the subscription. If you're on the fence, get off and buy them!!!

Have A Question? We Are Here To Help!
What are the ingredients?
  • Pup Plus contains pharmaceutical-grade Nicotinamide Riboside (NAD+ precursor), PQQ (mitochondrial builder), CoQ10 (ubiquinol form), Omega-3 DHA/EPA, Taurine, Astaxanthin, and natural liver flavoring. All ingredients are human-grade and third-party tested.
Can I use other products as well?
Yes! Pup Plus works synergistically with joint supplements, probiotics, and other wellness products. It addresses cellular aging—the root cause that other supplements don't target.
Is this safe for all breeds?
Yes. Pup Plus is safe for all breeds and sizes. Dose by weight for optimal results.
Does this replace my dog's other medications?
No. Pup Plus is a supplement, not a medication. Never stop prescription medications without consulting your veterinarian. Pup Plus works alongside conventional treatments.
Does Pup Plus cause any side effects?
Pup Plus is extremely well-tolerated. In rare cases, dogs may experience mild digestive adjustment during the first few days. This typically resolves quickly.
If I stop using the product, will my dog's symptoms return?
NAD+ levels will gradually decline again if supplementation stops. For sustained benefits, consistent daily use is recommended.
What is the manufacturing process?
Pup Plus is manufactured in a GMP-certified, FDA-registered facility in the USA. All ingredients are third-party tested for purity and potency.
How does it work?
Pup Plus restores NAD+ levels (the master molecule controlling cellular aging), rebuilds mitochondrial function, activates longevity genes, reduces inflammation, and supports organ health—addressing aging at the cellular level.
How often should I give it?
Daily, with breakfast. Consistency is critical for cellular rejuvenation.
Can I give it to puppies?
Pup Plus is designed for dogs age 7+ experiencing NAD+ decline. Puppies have naturally high NAD+ levels and don't need supplementation.
How long does one bottle last?
One 30mL bottle lasts approximately 30 days for a medium-sized dog (25-50 lbs).
How should I store Pup Plus?
Store in a cool, dry place away from direct sunlight. Refrigeration is not required.
Is Pup Plus scientifically backed?
Yes. The ingredients in Pup Plus are supported by over 300+ peer-reviewed studies on NAD+, mitochondrial function, and mammalian longevity—including research from Harvard, MIT, and leading veterinary institutions.
Is my payment information secure?
Your data is transferred via a secure SSL encrypted checkout, therefore is subject to the latest security standards. The transmission of your data does not represent a risk at any time. Your security is our highest priority!
Is there any recurring charge?
You will only be charged once and will be protected by our 180-day guarantee, with no hidden fees whatsoever.
What is included in the set?
Your order includes Pup Plus™ Anti-Aging NAD+ Drops (30mL bottle), dosing instructions, and access to our Dog Longevity Club resources.
How does our guarantee work?
Try Pup Plus risk-free for 180 days. If you're not completely satisfied, email us for a full refund—no questions asked.
Shipping & Returns
How long does the shipping take? 

The delivery time to USA, Canada, Ireland, New Zealand, Australia, and the United Kingdom is currently 3 to 9 business days. You can find the details in our delivery information. 

How can I track my order? 

As soon as we ship your package, you will receive an email with a tracking number. You can easily track your order on our website by clicking "Track Your Order" on our official site, pup-plus.com 

When do I get my money back after returning the item? 

Your refund will be released as soon as we have processed your return. The amount will be refunded to the account or card that was used for the purchase. Please note that credit card refunds may take longer to process. We try to process everything for you as quickly as possible, however, individual banks may take longer to process refunds.

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